Lions picks or NFL predictions, you need to see the NFL betting advice from the SportsLine Projection Model. Cowboys odds via SportsLine consensus, while the over/under for total points scored is 52.5, up a point from the opening line. The Cowboys are favored by 5.5 points in the latest Lions vs. Detroit has the league's 15th-best defense, allowing 325.5 yards per game, while Dallas is seventh at 299.7. The game from AT&T Stadium in Arlington, Texas, will get underway at 8:15 p.m. The Cowboys (10-5), who have already clinched a postseason berth, have fallen one game behind the Philadelphia Eagles for the NFC East lead. The win locked up their first division crown since 1993. The Lions (11-4), the NFC North Division champions, have won three of their last four games, including a 30-24 win over the Minnesota Vikings on Sunday. The Dallas Cowboys will look to snap a two-game losing streak, while the Detroit Lions will look to win their third game in a row when they meet in a key NFC matchup on Saturday night.